Early on I started trying various supplements and medications to see if anything helped my pain, muscle stiffness or the dreaded fibro fog. I've found a couple of things that help:
Malic Acid: this helps with muscle pain, sleeping and the fibro fog. I take at least 2,400 mg of Malic Acid with magnesium.
D-Ribose: this helps with muscle pain and I take about 2,000 mg a day of this
SAM-e: this I take for depression and my energy levels. I take 800 mg a day of this
Savella is a prescription medication for fibro. A lot of people can't take it due to the nausea that effects most people while they are getting used to it. I took an anti-nausea drug with it for the first couple of weeks to help me stick with it.
Flexeril: I take this muscle relaxer for sleep. It helps me fall asleep and to stay asleep through the night as early morning waking is often a problem for me.
I also take vitamin B and D supplements.
Lastly, if I'm still having problems with pain I take a 600 mg prescription Ibuprofen and 1/2 of a Vicodin. I've found that the combination of the two works better than either by itself or even an entire Vicodin.
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